Sebastian Grosicki Selected Research

ofatumumab

1/2020	A 5-year follow-up to evaluate the efficacy and safety of ofatumumab added to fludarabine and cyclophosphamide in patients with relapsed chronic lymphocytic leukemia: final analysis of the COMPLEMENT 2 trial.
12/2019	Ofatumumab maintenance prolongs progression-free survival in relapsed chronic lymphocytic leukemia: final analysis of the PROLONG study.
11/2018	Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia: A cross-trial comparison of phase 3 studies.
1/2017	Ofatumumab plus fludarabine and cyclophosphamide in relapsed chronic lymphocytic leukemia: results from the COMPLEMENT 2 trial.
9/2016	Health-related quality of life and patient-reported outcomes of ofatumumab plus chlorambucil versus chlorambucil monotherapy in the COMPLEMENT 1 trial of patients with previously untreated CLL.
1/2016	Phase III, randomized study of ofatumumab versus physicians' choice of therapy and standard versus extended-length ofatumumab in patients with bulky fludarabine-refractory chronic lymphocytic leukemia.
1/2016	A phase 2, multicenter study investigating ofatumumab and bendamustine combination in patients with untreated or relapsed CLL.
10/2015	Ofatumumab maintenance versus observation in relapsed chronic lymphocytic leukaemia (PROLONG): an open-label, multicentre, randomised phase 3 study.
6/2015	Ofatumumab for the treatment of chronic lymphocytic leukemia.
5/2015	Chlorambucil plus ofatumumab versus chlorambucil alone in previously untreated patients with chronic lymphocytic leukaemia (COMPLEMENT 1): a randomised, multicentre, open-label phase 3 trial.

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Sebastian Grosicki Research Topics

Disease

31	Multiple Myeloma 10/2022 - 05/2011
17	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 01/2015
9	Disease Progression 01/2022 - 01/2015
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2021 - 02/2008
8	Neutropenia 12/2019 - 05/2015
7	Fatigue 11/2020 - 12/2015
5	Peripheral Nervous System Diseases (PNS Diseases) 10/2021 - 05/2011
5	Leukemia 08/2021 - 02/2008
5	Hemorrhage 12/2020 - 12/2015
5	Infections 11/2018 - 02/2002
4	Thrombocytopenia (Thrombopenia) 11/2020 - 02/2016
3	Neoplasms (Cancer) 01/2022 - 01/2018
3	Pneumonia (Pneumonitis) 11/2020 - 01/2018
3	Febrile Neutropenia 05/2020 - 01/2018
3	Anemia 11/2018 - 12/2015
2	Frailty 11/2021 - 01/2021
2	Pain (Aches) 10/2021 - 01/2018
2	Atrial Fibrillation 12/2020 - 01/2020
2	Cough 11/2020 - 12/2015
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 07/2018 - 01/2018
2	Vomiting 01/2018 - 12/2015
1	Malnutrition (Nutritional Deficiencies) 01/2022
1	Lymphoma (Lymphomas) 01/2021
1	Waldenstrom Macroglobulinemia (Macroglobulinemia) 12/2020
1	Hypertension (High Blood Pressure) 12/2020
1	Bronchitis 11/2020
1	Respiratory Tract Infections (Respiratory Tract Infection) 11/2020
1	Hepatitis B 05/2020
1	Sepsis (Septicemia) 05/2020
1	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 05/2020
1	Refeeding Syndrome 01/2020
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2020
1	Hyperglycemia 11/2018
1	Fever (Fevers) 01/2018
1	Myocardial Infarction 01/2018
1	Retinal Vein Occlusion 01/2018
1	Inflammation (Inflammations) 01/2018
1	Thrombosis (Thrombus) 01/2018
1	Acute Kidney Injury (Acute Renal Failure) 01/2018
1	Weight Loss (Weight Reduction) 01/2018
1	Chronic Disease (Chronic Diseases) 01/2018
1	Residual Neoplasm 01/2018
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2016
1	Diarrhea 12/2015
1	Nausea 12/2015

Drug/Important Bio-Agent (IBA)

16	Bortezomib (Velcade)FDA Link 01/2022 - 05/2011
14	Dexamethasone (Maxidex)FDA LinkGeneric 06/2022 - 08/2015
10	ibrutinibIBA 01/2022 - 12/2015
10	ofatumumab FDA Link 01/2020 - 05/2015
8	daratumumabIBA 10/2022 - 01/2018
7	Chlorambucil (Leukeran)FDA Link 01/2022 - 05/2015
7	Rituximab (Mabthera)FDA Link 01/2022 - 01/2015
6	elotuzumabIBA 06/2022 - 08/2015
6	Lenalidomide (CC 5013)FDA Link 06/2022 - 08/2015
6	selinexorIBA 01/2022 - 11/2020
6	Cytarabine (Cytosar-U)FDA LinkGeneric 08/2021 - 02/2008
6	Cladribine FDA LinkGeneric 08/2021 - 02/2008
6	fludarabineIBA 01/2020 - 05/2008
5	Bendamustine Hydrochloride FDA Link 01/2022 - 01/2016
5	Prednisone (Sone)FDA LinkGeneric 11/2021 - 06/2014
5	Melphalan (Alkeran)FDA LinkGeneric 11/2021 - 06/2014
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 01/2017
3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 02/2016
3	Proteasome InhibitorsIBA 11/2020 - 11/2018
3	Pharmaceutical PreparationsIBA 05/2020 - 05/2011
3	Monoclonal AntibodiesIBA 11/2018 - 06/2014
2	zanubrutinibIBA 01/2022 - 12/2020
2	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2020 - 02/2008
2	Complement C2 (Complement Component 2)IBA 01/2020 - 01/2017
2	ixazomibIBA 01/2019 - 01/2019
2	Daunorubicin (Cerubidine)FDA LinkGeneric 07/2012 - 05/2008
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 02/2008 - 02/2002
1	DNA (Deoxyribonucleic Acid)IBA 11/2021
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 11/2021
1	carfilzomibIBA 01/2021
1	Exportin 1 ProteinIBA 01/2021
1	umbralisibIBA 01/2021
1	Enoxaparin (Lovenox)FDA LinkGeneric 12/2020
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2020
1	pomalidomideIBA 11/2018
1	serum P-component (CIt)IBA 11/2018
1	Angiogenesis InhibitorsIBA 02/2018
1	Thrombopoietin ReceptorsIBA 01/2018
1	eltrombopag FDA Link 01/2018
1	AnthracyclinesIBA 04/2017
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 12/2016
1	Biological ProductsIBA 01/2016
1	ChromatinIBA 12/2015
1	EpitopesIBA 06/2015
1	Proteins (Proteins, Gene)FDA Link 06/2015

Therapy/Procedure

31	Therapeutics 01/2022 - 02/2002
5	Drug Therapy (Chemotherapy) 01/2022 - 02/2002
4	Stem Cell Transplantation 06/2022 - 01/2018
2	Intravenous Administration 10/2022 - 05/2011
2	Transplantation 06/2022 - 10/2015
2	Induction Chemotherapy 01/2020 - 04/2017
2	Remission Induction 05/2008 - 02/2002
1	Platelet Transfusion (Blood Platelet Transfusions) 01/2018
1	Catheters 01/2018
1	Hematopoietic Stem Cell Transplantation 10/2015